How long does it take for penicillin to work on sore throat Home › Forums › World of Warcraft › How long does it take for penicillin to work on sore throat This topic has 0 replies, 1 voice, and was last updated 7 years, 1 month ago by spervaclase1987. You must be logged in to reply to this topic. Log In Username: Password: Keep me signed in Log In